Altman DG, Machin D, Bryant TN, Gardner MJ (Eds) (2000) Statistics with confidence, 2 nd ed.2007 except when the predicitive value is 0 or 100%, in which case a Clopper-Pearson confidence interval is reported. 2000.Ĭonfidence intervals for the predictive values are the standard logit confidence intervals given by Mercaldo et al. Sensitivity, specificity, disease prevalence, positive and negative predictive value as well as accuracy are expressed as percentages.Ĭonfidence intervals for sensitivity, specificity and accuracy are 'exact' Clopper-Pearson confidence intervals.Ĭonfidence intervals for the likelihood ratios are calculated using the 'Log method' as given on page 109 of Altman et al. When you upgrade the software, the sample data files may be overwritten by new versions of these files.$$ Accuracy = Sensitivity imes Prevalence + Specificity imes (1 - Prevalence) $$

When you run the software for the first time, several MedCalc sample data files will be copied into your documents folder, typically into You should re-enable it as soon as installation has been completed. Temporarily disabling your anti-virus program may help if you're having trouble with your installation. Anti-virus programs can sometimes interfere with the MedCalc installation process.How to determine whether a computer is running a 32-bit version or 64-bit version of the Windows operating system (link to Microsoft website).If you want to install the 64-bits version and you have a 32-bits MedCalc version already installed, you should first remove that older MedCalc version through your Windows control panel.Then execute medcalcsetup.msi and follow the instructions for the installation procedure. If you have previously installed MedCalc, you must close any open (running) copy of MedCalc first.The MedCalc installation files are suitable for new installations only as well as software updates.

MedCalc 22 can read all previous file formats but when saved, the new file format is used. Important: files saved in MedCalc version 22 cannot be read by previous MedCalc versions.

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